Anti-cancer effects of melatonin

Every cell in the body, including cancer cells have receptors for melatonin. Known as the chemical expression of darkness, it tells our cells that it is night time, and time to stop.

  • Powerful antioxidant.
  • Activates the immune system.
  • It prevents cell mobility that causes cancer to spread
  • Prevents the growth of blood vessels that provide nourishment for cancer cells.
  • Blocks oestrogen’s cancer stimulating effects
  • Blocks the ability of tumours ability to stimulate localised production of oestrogen.
  • It interferes with the cancer cell cycle leading to cancer cell death
  • Blocks Telomerase’s ability to make cancer cells immortal.
  • Promotes normal daily rhythms which helps prevent cancer and prevents the cancer promoting action of certain genes.
  • Accelerates the process by which immature cells become differentiated mature cells- preventing cancer.
  • Melatonin alters fat metabolism and interferes with the ability of many tumours to use the fatty acid linoleic acid as a growth signal, this causes tumour metabolism and growth to be shut down.
  • Blocks uptake of glucose (the Warberg effect) by cancer cells.
  • Melatonin has been shown to greatly enhance the effectiveness of tamoxifen a drug used to treat breast cancer.
  • A robust melatonin rhythm has also been shown to enhance the effectiveness of chemotherapy (Blask- citation needed)

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